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| 别名: | 关联848193-73-7 | ||
|---|---|---|---|
| Cas号: | 848193-72-6 | 物化性质: | |
| 分子式: | C14H15ClN2O | 熔点: | |
| 分子量: | 262.73 | 沸点: | |
| EINECS编号: | 密度: | ||
| MDL号: | MFCD11045286 | 储存条件: | 2-8°C |
| 技术规格说明书 | |||
|
| 货号 | 规格 | 可用库存 | 销售价(RMB) | 您的折扣价(RMB) | 数量 | 加入购物车 |
|---|---|---|---|---|---|---|
| C921209-1mg | 97% (chiral, HPLC) | 上海：现货 山东：- 广东：- 重庆：- 河北：- |
1,530.00 | 加入购物车 | ||
| C921209-5mg | 97% (chiral, HPLC) | 上海：现货 山东：- 广东：- 重庆：- 河北：- |
5,999.00 | 加入购物车 | ||
| C921209-25mg | 97% (chiral, HPLC) | 上海：现货 山东：- 广东：- 重庆：- 河北：- |
17,999.00 | 加入购物车 |
| 用途: | CHIC-35 is cell-permeable, metabolically stable, and very potent inhibitor of SIRT1; IC50 of S-isomer is 60 nM; IC50 of mixed isomers is 124 nM. There is no inhibition of SIRT3 or HDAC. The IC50 for SIRT2 is 2.77 μM. Sirtuins are protein deacetylases, which represent a new class of histone deacetylases (HDAC) involved in gene silencing. SIRT modulators are potential therapeutics for cancer, diabetes, muscle differentiation, heart failure, neurodegeneration, and aging. |
|---|---|
| 储存条件: | 2-8°C |
| 颜色: | 白色固体 |
