别名: | |||
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Cas号: | 108392-02-5 | 物化性质: | |
分子式: | C39H72O8PNa | 熔点: | |
分子量: | 722.95 | 沸点: | |
EINECS编号: | 密度: | ||
MDL号: | 储存条件: | -20°C | |
技术规格说明书 中文版MSDS 英文版MSDS |
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货号 | 规格 | 可用库存 | 销售价(RMB) | 您的折扣价(RMB) | 数量 | 加入购物车 |
---|---|---|---|---|---|---|
D864427-25mg | >99% | 上海:现货 山东:现货 广东:- 重庆:现货 河北:- |
395.00 | 加入购物车 | ||
D864427-100mg | >99% | 上海:现货 山东:现货 广东:现货 重庆:现货 河北:现货 |
794.00 | 加入购物车 | ||
D864427-500mg | >99% | 上海:现货 山东:现货 广东:现货 重庆:- 河北:现货 |
2,100.00 | 加入购物车 | ||
D864427-1g | >99% | 上海:现货 山东:现货 广东:现货 重庆:- 河北:- |
3,615.00 | 加入购物车 |
用途: | Phosphatidic Acid, Dioleoyl has been shown to activate PKC α, ε, or ζ isotypes in the cytosol of COS cells. This compound not only stimulates PKC-ζ-mediated phosphorylation of distinctive substrates, but additionally causes an upward shift in electrophoretic mobility of PKC &zeta. Furthermore, experiments have reported Phosphatidic Acid to be generated by hydrolysis of phosphatidylcholine, via phospholipase D (PLD). Mechanistic studies suggest activation of PLD by insulin and consequential generation of Phosphatidic Acid which then induces Raf-1 translocation to cell membranes. Raf-1 is an essential component to the mitogen-activated protein kinase cascade, and once it has crossed over to the plasma membrane, other factors may activate it through phosphorylation. |
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储存条件: | -20°C |
颜色: | 白色到灰白色到浅黄色固体 |