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| 别名: | |||
|---|---|---|---|
| Cas号: | 129425-81-6 | 物化性质: | |
| 分子式: | C14H14O5S | 熔点: | |
| 分子量: | 294.32 | 沸点: | |
| EINECS编号: | 密度: | ||
| MDL号: | 储存条件: | -20°C，密闭，干燥 | |
| 技术规格说明书 中文版MSDS 英文版MSDS | |||
|
| 货号 | 规格 | 可用库存 | 销售价(RMB) | 您的折扣价(RMB) | 数量 | 加入购物车 |
|---|---|---|---|---|---|---|
| M910697-10mg | 97% | 上海：现货 山东：现货 广东：现货 重庆：- 河北：- |
864.00 | 加入购物车 | ||
| M910697-50mg | 97% | 上海：现货 山东：现货 广东：现货 重庆：- 河北：- |
2,382.00 | 加入购物车 | ||
| M910697-250mg | 97% | 上海：现货 山东：- 广东：- 重庆：- 河北：- |
5,886.00 | 加入购物车 | ||
| M910697-1g | 97% | 上海：现货 山东：- 广东：- 重庆：- 河北：- |
14,710.00 | 加入购物车 | ||
| M910697-bulk | 97% | POA | POA | POA | 价格咨询 | |
| 用途: | MSA-2 is an orally available human STING agonist.MSA-2 is bound to STING as a noncovalent dimer. Extensive experimental analysis indicates that MSA-2 predimerization is required for binding. Acidic tumor microenvironments favor permeable, uncharged MSA-2. Intracellular MSA-2 is "trapped" and accumulation drives MSA-2 dimerization, preferentially activating STING intratumorally. Orally dosed MSA-2 is well tolerated in mice, exhibiting STING-dependent antitumor activity, as monotherapy and combined with antibodies against PD1 (anti-PD1). |
|---|---|
| 储存条件: | -20°C，密闭，干燥 |
| 颜色: | 浅黄色到棕色固体 |
