别名: | |||
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Cas号: | 2375420-34-9 | 物化性质: | |
分子式: | C15H9F2N5O3 | 熔点: | |
分子量: | 345.26 | 沸点: | |
EINECS编号: | 密度: | ||
MDL号: | 储存条件: | -20°C,密闭,干燥 | |
技术规格说明书 |
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货号 | 规格 | 可用库存 | 销售价(RMB) | 您的折扣价(RMB) | 数量 | 加入购物车 |
---|---|---|---|---|---|---|
S910710-5mg | 97% | 上海:现货 山东:- 广东:- 重庆:- 河北:- |
1,637.00 | 加入购物车 | ||
S910710-25mg | 97% | 上海:现货 山东:- 广东:- 重庆:- 河北:- |
5,751.00 | 加入购物车 | ||
S910710-bulk | 97% | POA | POA | POA | 价格咨询 |
用途: | SR-717 is a non-nucleotide, small-molecule STING agonist and functions as a direct cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) mimetic that induces the same "closed" conformation of STING.SR-717 functions as a direct cyclic guanosine monophosphate–adenosine monophosphate (cGAMP) mimetic that induces the same “closed” conformation of STING. SR-717 displayed antitumor activity; promoted the activation of CD8+ T, natural killer, and dendritic cells in relevant tissues; and facilitated antigen cross-priming. SR-717 also induced the expression of clinically relevant targets, including programmed cell death 1 ligand 1 (PD-L1), in a STING-dependent manner. |
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储存条件: | -20°C,密闭,干燥 |
颜色: | 白色固体 |